Head of Platform Development

Role Description:

BigHat Biosciences is seeking an exceptional, self-motivated scientist with an engineering mindset to lead the development of BigHat’s high-throughput, automated platform for producing and characterizing antibodies. Responsibilities include:

  • Own the development and optimization of the BigHat work cell for antibody production, purification and characterization with high throughput and low cost and consumable use.
  • Lead the sourcing, onboarding, validation, and operation of cutting-edge assays to produce and characterize antibody biophysical properties (e.g. stability, solubility).
  • Lead process engineering efforts to evaluate, optimize and integrate platform components for throughput, efficiency, and cost.
  • Critically evaluate and re-design the status quo from cell-free synthesis through ex-vivo antibody characterization to accelerate BigHat’s platform capabilities
  • Collaborate closely with BigHat executives, AI/ML, and other team members to ensure a tight linkage between the experimental and machine learning platform components.
  • Nice-to-haves include antibody or protein engineering background; experience developing cell-free protein extracts, programming skills, automation experience


Compensation will include a competitive pay package, benefits, and equity commensurate with being an early employee at a growth-oriented startup. Job title and compensation will be set based on experience, so we encourage applicants with a diverse range of experiences to apply.


About You: You have a stellar track record at top-tier institutions or companies, a strong scientific background (PhD) and publication record in molecular biology or biochemistry, fluency with protein expression, purification, and characterization techniques, and 3+ years of hands-on technical development experience such as assay development and process engineering; excellent communication skills; thrives in a fast-paced environment helping to launch, operate and grow a high-potential startup. If you love tinkering, optimizing and diving headfirst into diverse, highly technical projects then BigHat could be the right home for you. 


Please reach out to careers@bighatbio.com to start a conversation about this role.